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Electrochemical Detection of Paracetamol and Iohexol Using a Boron-Doped Diamond Anode Modified with Gold Particles

Persistent organic pollutants such as pharmaceuticals (iohexol and paracetamol) released into the environment is an environmental problem. Thus our objective is to propose an effective and less expensive method for the determination of their concentrations in the environment. In this work the detection and quantification of pharmaceuticals (iohexol and paracetamol) were performed using cyclic voltammetry and differential pulse voltammetry (DPV). The anode used is a boron-doped diamond electrode (BDD) modified with gold particles (Au-BDD). The characterization of the Au-BDD electrode surface by scanning electron microscopy coupled to energy dispersive spectroscopy and by the electrochemical method (cyclic voltammetry) showed the presence of gold particles uniformly distributed on the anode surface. DPV method allowed to obtain two calibration curves for iohexol and paracetamol concentrations ranging respectively from 4 µM to 67.42 µM and from 0.8 µM to 22.943 µM. The limits of detection are respectively 1.13 µM and 0.045 µM for iohexol and paracetamol. These results show that the presence of gold particles on the anode surface improved the detection of paracetamol. These pharmaceuticals were detected in an ionic environment and it was noted that the interference phenomenon was very negligible during the detection of these two pharmaceuticals. This shows that our anode can be used to determine PCM and IHX concentrations in highly charged media.

Detection, Paracetamol, Iohexol, Gold, Voltammetry

APA Style

Koffi Konan Sylvestre, Kambiré Ollo, Gnamba Corneil Quand-même, Kimou Kouakou Jocelin, Berté Mohamed, et al. (2023). Electrochemical Detection of Paracetamol and Iohexol Using a Boron-Doped Diamond Anode Modified with Gold Particles. American Journal of Applied Chemistry, 11(4), 103-111.

ACS Style

Koffi Konan Sylvestre; Kambiré Ollo; Gnamba Corneil Quand-même; Kimou Kouakou Jocelin; Berté Mohamed, et al. Electrochemical Detection of Paracetamol and Iohexol Using a Boron-Doped Diamond Anode Modified with Gold Particles. Am. J. Appl. Chem. 2023, 11(4), 103-111. doi: 10.11648/j.ajac.20231104.12

AMA Style

Koffi Konan Sylvestre, Kambiré Ollo, Gnamba Corneil Quand-même, Kimou Kouakou Jocelin, Berté Mohamed, et al. Electrochemical Detection of Paracetamol and Iohexol Using a Boron-Doped Diamond Anode Modified with Gold Particles. Am J Appl Chem. 2023;11(4):103-111. doi: 10.11648/j.ajac.20231104.12

Copyright © 2023 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License ( which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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