Volume 3, Issue 1, February 2015, Page: 14-20
Isolation, Structural Elucidation, and Bioactivity Studies of Leaf Extract of Vernonia Amygdalina
Muluye Melak Zenebe, Department of Chemistry, College of Natural and Computational Science, University of Gondar, Gondar, Ethiopia
Bitew Kassaw Dessie, Department of Chemistry, College of Natural and Computational Science, University of Gondar, Gondar, Ethiopia
Getachew G/Mariam W/Hana, Department of Chemistry, College of Natural and Computational Science, University of Gondar, Gondar, Ethiopia
Adhena Ayaliew Werkneh, Department of Chemistry, College of Natural Science, Jigjiga University, Jigjiga, Ethiopia
Received: Jan. 1, 2015;       Accepted: Jan. 10, 2015;       Published: Jan. 21, 2015
DOI: 10.11648/j.ajac.20150301.13      View  3409      Downloads  413
Abstract
Vernonia Amygdalina (VA) is a tropical African plant of the Asteraceae family and is occasionally cultivated for its medicinal uses, which include as a treatment for diarrhea, skin wounds, fever mastitis and worms infection. The aim of this study is to isolate and elucidate the structure of some of the chemical constituents from the leaf of Vernonia Amygdalina and its bioactivities. The methanol extract of Vernonia Amygdalina, after repeated chromatography led to the isolation of a different compound, one of this compound (MM-4) is partially characterized based on the spectral data (IR, 1H NMR, 13C NMR, and DEPT) and extracts from Vernonia Amygdalina has been shown to have antimicrobial activity.
Keywords
Vernonia Amygdalina, Bioactivity, Phytochemical Investigation
To cite this article
Muluye Melak Zenebe, Bitew Kassaw Dessie, Getachew G/Mariam W/Hana, Adhena Ayaliew Werkneh, Isolation, Structural Elucidation, and Bioactivity Studies of Leaf Extract of Vernonia Amygdalina, American Journal of Applied Chemistry. Vol. 3, No. 1, 2015, pp. 14-20. doi: 10.11648/j.ajac.20150301.13
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